Multi-Sided Compression Performance Assessment of ABI SOLiD WES Data

Data storage is a major and growing part of IT budgets for research since many years. Especially in biology, the amount of raw data products is growing continuously, and the advent of the so-called “next-generation” sequencers has made things worse. Affordable prices have pushed scientists to massively sequence whole genomes and to screen large cohort of patients, thereby producing tons of data as a side effect. The need for maximally fitting data into the available storage volumes has encouraged and welcomed new compression algorithms and tools. We focus here on state-of-the-art compression tools and measure their compression performance on ABI SOLiD data.